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-   -   low dose naltrexone (http://forums.marrowforums.org/showthread.php?t=1313)

Lbrown Tue May 31, 2011 12:14 PM

Good luck Gustav!

Deb

suntime Sat Jun 4, 2011 04:38 AM

5 days ago I modified my dosage of LDN - meaning that I lowered it. The basic principle behind lowering the dosage is that we're talking about 'homeopathic' quantities. Thus, the less 'material' the more information, I thought.

Also, I read somewhere that a woman found out that she didn't make any use of the original - or widely recommended - dosage, which is 4.5mg. She tried 2.5 - 3.0mg and it worked a lot better for her (with her SM).

So 5 days have passed with my 'new' 3.0mg LDN. Something has definitely changed, as I sleep a lot better and have really vivid dreams - so vivid that I can't decide what is real.

I came in the hospital 2 days ago, the 5-week treatment has begun. I am hoping for the best... while being content with what I have :)

Blessings to All,
sun

Marlene Wed Jul 13, 2011 07:42 AM

New study on LDN...
 
and ovarian cancer.

http://www.sciencedaily.com/releases...0712143012.htm

Lbrown Wed Jul 13, 2011 08:52 AM

Interesting. I wonder what "nude mice" are? Also have to be careful about extrapolating mice studies to humans. My mother in law died of ovarian cancer less than 2 years ago. She was stage 4 when it was diagnosed and had no symptoms up until then. The chemo made sure the strong cancer cells survived.

Deb

Marlene Wed Jul 13, 2011 09:25 AM

I think nude mice are hairless. And yes, mice vs human is an issue. Not sure why they have to test it on mice though since it's in use in humans today.

Lbrown Wed Jul 13, 2011 09:29 AM

It may not be ethical to test on people with ovarian cancer. What is the significance of nude mice I wonder? I'm gonna go look it up.

Deb

Lbrown Wed Jul 13, 2011 09:37 AM

Couldn't find much out about nude mice so far, but have a look at this:

Strains Of Laboratory Mice More Varied Than Previously Thought
http://www.sciencedaily.com/releases...0730092539.htm

"if one is studying mouse strains for responses to particular drugs, you make assumptions that the strains have certain pedigrees. If they don't, what you are doing may not mean anything."

Wow.

Marlene Wed Jul 13, 2011 10:29 AM

And I just saw this Huffington Post re humanized mice for drug testing. Wild stuff.

http://www.huffingtonpost.com/2011/0..._n_896539.html

Lbrown Wed Jul 13, 2011 10:35 AM

Well, maybe it'll have some useful applications. But human and mice immune systems are quite different. By only looking at how the liver deals with drugs, they are being very narrow.


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