Mona,
I'm sorry to hear about your mom's diagnosis.
I am not in the medical field, but have learned from experience. Here is my interpretation. I hope it helps...
<Moderately hypercellular bone marrow (85%)>
Her marrow is making an excessive amount of cells that are most likely not functioning like normal.
<decreased M?E ratio>
This is the ratio of myeloid cells to erythroid cells. The myeloid cells are the high level precursors to all the blood cells (RBCs, WBCs, and platelets). The erythroid cells are the precursors to RBCs. This ratio should be around 2:1.
<due to increased erythroid series showing mild megaloblatoid changes.>
There are lots of RBC precursors, some are misshaped.
<The myeloid series shows left shift>
There are more immature bone marrow cells seen than fully mature ones.
<Megakaryoytes show focal dysplastic features>
There are misshaped platelet precursors.
<Plasma cells and eosinophils are unremarkable>
No problems seen with these cells.
<Focal fibrosis is seen>
Some scarring is seen in the marrow. If they did a reticulin stain it will indicate the level of fibrosis.
<The morphology is consistent with MDS. Iron stain and clinical correlation are recommended".>
It is true. All these things can be seen with MDS, especially in a hypercellular marrow.
Did they also do a peripheral blood smear? It is probably a good thing if blasts are not mentioned in the BMB.
I'd recommend checking out the AA&MDS International Foundation's website. Recently I saw that the MDS conference from Cleveland Ohio was downloaded there. There are some excellent presentations on MDS basics as well as treatment options:
http://live.blueskybroadcast.com/bsb...=1418&CAT=1419
I wish you both the best!