Thankyou Birgitta.
I read both of them, and it appears each time the complex text is a bit easier to read!

Yes I know it seems the syndrome is so very complicated. Also it seems in the same individual the situation changes with time.
What does it actually mean to have the tumor-suppressing gene hypermethlyation - does it mean that the proliferation is checked, that the proliferated cells quickly die, or the sequence/rate of cell division to cell death is out of order, or something like this?
But is this the cause or the symptom?