You made me google elevated liver enzymes after stem cell transplant and I came across this recent article.
I'm also curious because I had just asked about my husband's elevated Ferritin level.
Good luck and let us know what the doctor says.
http://www.hindawi.com/journals/ah/2010/345756.html
Review Article
Iron Overload in Patients Undergoing Hematopoietic Stem Cell Transplantation
Vinod Pullarkat
Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Medical Center, 150 East Duarte Road, Duarte, CA 91010, USA
The following paragraph is from this section ...
"5. Iron Overload in the Post-HSCT Period"
"...Iron overload is known to contribute to the etiology of liver dysfunction chiefly manifesting as elevated transaminases, a common chronic complication occurring in 50%–72% of patients [62, 63]. Iron overload therefore can mimic exacerbation of hepatic GVHD following HSCT, leading to unnecessary continuation or intensification of immunosuppressive therapy [64]. In a study assessing the role of liver biopsy in evaluating the cause of elevated transaminases in post-HSCT patients, 33% of biopsies had evidence of iron overload and no other pathologic findings [63]. Normalization in liver enzymes has been demonstrated with phlebotomy and iron chelation therapy [64, 65]. The role of persistent iron overload in infections that occur late after HSCT, particularly in patients with chronic GVHD requires further investigation..."
Quote:
Originally Posted by tserdogan
Hi,
i am very anxious ,My last liver enzymes are thirty times more.i will visit my transplant doctor tomorrow,and i hope i will learn what is going on my enzymes(Ast;Alt) |