Hi cheri and Greg,
When they started to use Thalidomide for MDS they gave the poor patients very high doses – up to 1000 mg/day
. Of cause the patients couldn’t tolerate that and very few improved.
Now they look at the doses that have been OK for patients with the disease Myelofibrosis – that is 50 mg/day + Prednisone 30 mg/day tapered during 3 months.
Here they report 10 studies where 8 to 59 % of the patients improved:
http://online.haematologica.org/EHA1...se&-recid=3370
I have found abstracts for 6 of these studies. Here is info about the study with the best results:
http://onlinelibrary.wiley.com/doi/1...817.x/abstract
Kind regards
Birgitta-A