Hi Cheri,
TPA found in croton oil has been used in Asia during a very long time for different diseases for example haematological cancer. The only reference I can find where they use TPA + Dexamethasone + choline magnesium trisalicylate is this Patent Application:
http://www.freshpatents.com/-dt20110...0110034425.php
RO5045337 is made by Roche. This drug inhibits the oncoprotein (cancer protein) MDM2. MDM2 is overproduced in many human tumors. MDM2 impairs p53 function. P53 is a very important tumor suppressor gene.
http://www.cmod.org/images/CMOD_Pres...017%202010.pdf
Both studies seem to be interesting. Hope you will be able to participate in one of them!
Kind regards
Birgitta-A