Hi Fellow MDS colleagues,
After a great response to Revlimid+Dacogen and Promacta from Feb 2011 to the end of May 2011 my counts started a rapid drop.
The platelets were the first to drop, often the case with Revlimid, and I found myself with platelets below 10 for 4 weeks in a row, the last being 5.
My doctor(s) recommended a battery of drugs to help the platelets: Nplate, IVIG, prednisone and Danazole. After 3 weeks the platelets are now at 74, a tremendous response. I had a good response in 2 weeks with the platelets at 28. We are not sure what med is causing the increase, I'm inclined to think it might be the Nplate.
My Hgb is still dropping but the rate of drop is decreasing so I'm looking for a turn around soon. We are retrying thalidomide but I'm not too confident since it's a 3rd attempt after being off of it for only 5 months. Hope to restart Dacogen soon.
I'm waiting for the the coaster to start uphill soon on all CBC counts.