Dear Ziad,
Very good counts

! No sign of that your father is refractory to platelets. You know all kinds of chemo can give tiredness. Then many patients get nausea even if they receive treatment to prevent that. It is important to try to eats well - many patients try special drinks with protein and vitamines.
When patients get Vidaza the adverse effects usually will come after the first cycles and the response later. More than 50% of the high risk MDS patients respond.
Don't worry about the iron overload - as you know we can have high ferritin levels during many years before we get symptoms from the liver or the heart.
Kind regards
Birgitta-A