I'm a patient NOT a doc, but bad reactions after PRBC transfusions (e.g., uncontrollable shivering, fevers, blood when urinating,etc.) would indicate a poor match of donor product.
YMMV but for me a pre-med set comprising 2 reg. tylenol, 2x25 benadryl, and IV 100ml hydrocortisone prevents bad reactions to PRBCs that are given but classed as "least incompatible."
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Ric: Low-risk MDS (blasts <4%); 4 cycles Revlimid no positive response; PRBC transfusion dependent; so far, 392'units' over 8 3/4 years; BMB #4 (15/04/01) shows evolution to AML (blasts 20-30%
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47,XY,del(5) (q22q35),+21[24][cp24]/46,XY(1).