Hi Patti,
As far as I understand Neupogen should give effect at once but if the bone marrow is very suppressed it can perhaps take longer time. Actually I don't think Dacogen is the best drug for Dean - his bone marrow can't stand that drug.
I think it is OK to take Neupogen daily during a long time but many patients get joint pain from that drug when they take it daily. I have been taking Neupogen daily during 9 days when I tried a drug for iron overload that made my white blood cells decrease very much.
You know you could learn to inject Neupogen - it is not difficult. Dean's doctor is really very nice and engaged when he treats Dean in his office 7 days a week

!
The problem with Revlimid is that the drug often decreases platelets initially. I am taking a relative to Revlimid called Thalidomide, that can decrease platelets too. When I started to take Thalidomide my platelets increased from 22 to 43 during 4 weeks (highest value 115) so we never know what effects a drug will have on our disease.
Kind regards
Birgitta-A