Hi Patti,
If you look at Revlimid they write:
"Since lenalidomide is primarily excreted unchanged by the kidney, adjustments to the starting dose of REVLIMID are recommended to provide appropriate drug exposure in patients with moderate or severe (CLcr <60 mL/min) renal impairment". They recommend 5mg/day.
http://www.revlimid.com/hcp/MDS-dosing.aspx
Then there are several studies that have reported better response when Revlimid is combined with a steroid in patients with myeloma, myelofibrosis and MDS.
I hope you and Dean managed to tell the doctor that Dean won't take 15mg Revlimid/day because of his impaired kidney function and weakness!
Kind regards
Birgitta-A