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Old Sat Oct 20, 2012, 02:04 PM
Birgitta-A Birgitta-A is offline
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Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Folic acid

Hi Jen,
As several members have written MDS patients don't have episodes like seizures more often than other persons.

Then there is a problem with folic acid - the vitamin is very important for the bone marrow and we need it but the drug is DNA methylating. It means that folic acid can put extra methyl groups to DNA. These methyl groups can increase the risk of cancer.

Vidaza and Dacogen are so called hypometylating drugs - they work by decreasing the mythyl groups.

Perhaps you should take 1 mg of folic acid/day (I do that) and not 5 mg/day.
Kind regards
Birgitta-A
73 yo, dx MDS Interm-1 2006. Positive results with Thalidomide + Prednisone.
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