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Cam,
The Mayo Clinic is an excellent MDS treatment center, so I'm glad you have that going for you.
Do you know what your blood count numbers are? One of ironies of MDS is that you can have a serious disease with very little clue that something is wrong. However, if your counts are low enough then you'll feel symptoms.
There was only a 25% chance that your sister would match you (it's a test for inherited blood antigens called HLA). Siblings are the best donors, other things being equal, so they get tested first. When you look for matches in the national bone marrow registry, the odds depend on whether you have an HLA type that is common in the overall population or whether you have a rare HLA type, as well as how many people with similar ancestry have joined the registry. There are a number of Marrowforums members who have not yet found a single match. My wife had 2 matches. It's great that you have hundreds of potential matches.
SLB mentioned the further testing they do. This has to do with the number of antigen "match points" they compare. A preliminary match might be on the 6 major antigens, and a person who matches you that well can be a perfectly good donor. But an ever better match (giving you an even better chance of a successful transplant) can be identified by testing for 10 or 12 match points. The more points that match, the better that donor is likely to be.
Did you have a talk with a Mayo Clinic hematologist about having a transplant vs. other choices, such as drug treatments? Perhaps it's clear to them why a BMT is the best choice based on what your tests showed. Perhaps you have a very high "blast count" (the number of blood cells that have not yet matured in your bone marrow). If you have questions about the treatment decision, now is the time to ask!
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