Hi Janire,
One of the concerns in the clinical trial for Promacta at NIH was an increase in blasts with MDS. My husband took it for about 4 months before coming off. It normalized his red cells and put his platelets over 100,000 so he had to stop taking it. Even after being off since 7/12, his platelets are in the 80,000's and his RBC is near normal. There has been no increase in blasts in his case.
Take care and God Bless,
Sally
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