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Old Thu Aug 22, 2013, 12:27 PM
Marlene Marlene is offline
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Join Date: Oct 2006
Location: Springfield, VA
Posts: 1,406
Hi Deb,

Serum B12 testing is the least accurate way to measure B12. And when you have your blood drawn, you need stop taking your supplement otherwise, you'll get a false reading. I've heard anywhere from 3 days to one week prior to testing.

A more comprehensive check is to have your MMA (methylmalonic acid) and homocysteine checked at the same time. There are other test which I think are newer and not well utilize yet and they are HoloTranscoblamamin and Unsaturated B12 binding capacity.

Regarding blood levels and tissue levels, I too agree there can be a difference. You also hit upon a key distinction...absorption vs utilization.

Glad to hear Exjade is gluten free.

M
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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