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EPO response
Marlene, her pre-treatment EPO was 126. Doc says 6-8 weeks is enough to see if she will benefit from it. This is the 2nd try with EPO, at a high dose of 60,000 weekly, and neupogen added from week3.
As she is transfusion dependent, response will be seen in terms of longer transfusion intervals/lower hb drops. After starting EPO, she had a drop of 15 points in the first 24 days and then suddenly 10 points in last 7 days. So dont know what to make of whether EPO is having benefit or not. She has also started with Vit K2+D3 in the last few weeks. Hope there is some collective benefit of the 2 therapies together.
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Mother age 79, dx MDS RCMD low risk del 20q April 2013, no response to EPO, Danazol. pRBC tx dependent - 2 units every 3-4 weeks, exjade Dec 2013 - Mar2014, restarted Dec 2014
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