[pdiitdelhi0204]

Thanx sir.I know we have to be confident for good result in my case.In my son case Doctor didn't try for ATG. Ther are saying for child below 5 years, if you got 10/10 donor, it will be better to go directly for MUD transplant in stead of ATG. Also, today Doctor said donor is 49 year old male.

Originally Posted by Neil Cuadra

This is great news. I hope it goes very smoothly for your son.

Depending on which statistics you look at for which patient populations, you find that graft versus host disease affects less than half of patients. GVHD risk factors include higher age of the recipient, higher age of the donor, a male recipient with a female donor who has had children, and of course the degree of mismatch between donor and recipient. You are on the "good side" for most of these factors.

Unrelated donor transplants are more and more common because they have been more and more successful. They have always been the most successful for children. One reason that the overall statistics are hard to interpret is because of improved transplant success. If 100% of transplants were successful and without GVHD, they'd start doing transplants for higher-risk patients, which would help more people but bring the success rate down. That's what happens over time.

The most common types of GVHD affect the skin, the liver, or the digestive system. Even when it occurs, it can be mild and temporary.

An 8/8 match means that they matched the most important 8 antigens. Additional antigens may or may not match. With a 10/10 match they have confirmed the match for another pair of antigens. So an 8/8 match might actually be an 8/10 match or a 9/10 match or a 10/10 match. In some cases they test 12 antigens, not just 6, 8, or 10, but the additional matches are less and less important. Other factors, like the ones I mention above, can be statistically more important for success.

Good luck!