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thank you
Thank you so much. Wasn't sure whether it was inexperienced doctor (AA and PNH are both rare enough that even hematologists don't encounter many cases). Karin was having her serum Cyclosporine levels monitored and first they increased the dosage from 575 mg to 600 mg because of that. But then her kidneys which had appeared healthy prior to immune suppression started to complain. Electrolytes all over the place and her Creatinine and GFR wrong. So they reduced the dose to 300, then 200, then off it. I had been hoping most of the kidney function was OK (read some papers on the Internet) and just the indicators were wrong, but seems that was not the case. I hope the horse ATG is sufficient because not many options left. I wish eltrombopag was approved since it is reported as shortening the time needed on Cyclosporine before marrow recovery.
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