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Vidaza
Hi pleasant1911,
Vidaza is not approved in Europé for low risk MDS because they have not showed so positive results as in high risk patients. I have seen studies with between 30 and 67 % response rate. Remember that it will take several cycles before response in many patients.
A fraction of MDS patients will respond to ATG. HLA-DR15 positivity (HLA means human leukocyte antigen), young age and short duration of red cell transfusion dependence seem to predict for a response to immunosuppressive therapy in MDS patients.
Gleevec is a wonderful drug for patients a kind of leukemia called CML but has not showed positive results in MDS patients.
Your father's symptoms seem to be similar to mine - I have severe myelofibrosis since dx 2006 when I was 67 yo. In fact my dx was MF the first year and I was tx dependent from dx. I got supportive care until 2010 when I started treatment with Thalidomide with positive result. The last year I have been treated with Revlimid. My HGB was 14.5 in April 2014 but is now decreasing.
Hi bailie,
Congratulations!!! Hope the SCT will be a success!
Kind regards
Birgitta-A
75 yo. Cromosome aberrations 12pdel and X-.
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