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There are a lot of studies out there about ideal dosing and time between cycles. I think the question that I have is what is your recovery cycle? I noticed that when I was on Vidaza that my recovery was late into the fourth week and into the new treatment cycle. Some people have seen 5 to 6 week cycles show better recovery due to the amount of marrow suppression, and others have seen that a lower dose for more days may be better.
Also as Chirley noted, some people don't see best responses until 9 or more cycles. Progression of your disease is the one indication that I have consistently seen as a reason to change over or stop.
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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