[Hopeful]

Hi,

I am really sorry to read that your dad is requiring such frequent transfusions. This is not a good sign. Does he have any other symptoms?

How much of an increase in counts is he seeing right after a transfusion?
Are they doing antibody screening/HLA matching for both his RBC's and platelets before each transfusion?
How long has he been getting transfusions?
What is his age?
Has he been tested for PNH?

If his clotting factor is good, they may be able to do a BMB right after a platelet transfusion. I use to have them when my platelets were in the low teens with no incident. However, if his platelets are much lower, there may be an issue.

I hope they can quickly find the cause of this. Be strong!