With a WBC that low, neupogen might be an option, but I know that some doctors were reluctant to use it because of the potential for creating a blast crisis. From what I remember reading, the increase in blasts resolved after discontinuing neupogen. I don't think any of the research was really definitive on this point, and may have been refuted. It may be worth talking to your doctor about it though. The combination of low HGB and low whites could make you pretty tired. I did pretty well energy-wise for 4 years with really low platelets but otherwise decent WBC and HGB. It wasn't until my whites dropped that I really experienced fatigue. I know that doesn't make a lot of sense, but it was the correlation that I drew at the time, and the doctor confirmed that when you reach the near zero neutrophil count is when you feel the most debilitated during transplant.
Also, a quick comment on RCMD versus RAEB-2 - RAEB-2 can have multi-lineage dysplasia, but is defined as having 5-19% blasts. RCMD is usually defined by multi-lineage dysplasia with less than 5% blasts.
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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