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Rarity, after further research I've come to the conclusion that it's almost impossible to make any sense of this on my own. On PubMed I found articles that directly contradict each other on the effect of having a TET2 mutation. Also, what kind of mutation - insertion, deletion? - and on one copy or both has an effect. And it depends on which other mutations one has and the order in which the mutations were acquired. So it's very complex and each person is really unique. I wouldn't add it to my list of worries post transplant and I'm not going to let myself worry about it pre-transplant, either.
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Joanne, 65F, 8/17 dx Primary MDS-EB1, Pancytopenia; 6/19 MPN w/CMML characteristics, dr calling it AML even w/blasts <20%; 7/19 Induction w/Vyxeos resulting in complete remission with incomplete blood count recovery.
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