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Mom hasn't had a bone marrow test in a few years.
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Nancy,
It's certainly true that Exjade isn't for everyone. Does your mother have pre-existing renal conditions that make her more at-risk?
You say she hasn't had a bone marrow biopsy in quite a while, but now her transfusions requirements are changing. That in itself points to changes in her bone marrow. I'm surprised that her doctor wouldn't want to take another look at her marrow to see if there were any clues about how her disease is progressing. Has this been discussed? Given that her platelet and WBC counts are good, maybe you are dealing with something that is not really MDS. Only a bone marrow biopsy can confirm the diagnosis is still accurate.
Regards,
Ruth