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Old Tue Aug 5, 2008, 10:33 AM
sophia68 sophia68 is offline
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Join Date: Jul 2008
Location: Florida
Posts: 23
Quote:
Originally Posted by Birgitta-A View Post
Hi Sophia,
Hope your father is receiving an effective antibiotic drug - when I had neutropenic fever I got Tazocin intrevenously with very good result.

I have never accepted any chemos since I am so afraid of the adverse effects like low platelets - mine are already very low (last count 37). I hoped that there would be new drugs for low platelets available but the first one called Nplate is not at all OK for MDS patients.

Chromosome aberrations are disruptions in the normal chromosomal content of a cell and very common in white blood cells in MDS patients. If your father has an aberration called 5q deletion Revlimid should be the best drug for him.

For the moment the most important issue for your father is the infection or infections. Is he not receiving Neupogen or a similar drug for his low white blood cells as well as antibiotics?
Kind regards
Birgitta-A
Hi Birgitta,

Yes, my father is on antiobiotics (not sure of the name).

Wow, your platelet count is very low. As of yesterday, my dad's platelet count was 242. His WBC 1.2, HGB 8.4. He seemed alot better yesterday. His breathing has improved. Chest xrays were negative for pneumonia (only a trace of fluid in the lungs). Fever was down to 37.6. I'm not sure if he's receiving neuprogen for the low WBC.

I found my dad's original bone marrow biopsy report which states no clonal chromosome abnormalities. He has RARS - Thrombocytosis and eosinophills present. From what I have researched dad is at a low risk for his MDS to progress to AML. If this is true, why would his hemo put him through inductive chemo?
__________________
Dad (83) DX w/MDS-RARS on 6/10/06.Prev treated w/Vidaza & Thalomid w/o success. Treated w/Decitabine w/some imprv discont after no resp. TX dep as of Aug'10 (evry 2-3 wks). Curr tkg Revlimid since Feb'11. Exjade since Apr'11. Recd lwr dsg decitabine on 6/6/11 in comb w/rev.
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