Hi run4peach1,
There are many articles about thrombocythemia and hydrea. Most of them are more tham 10 years old. Here is an abstract about thrombocythemia and cytoreductive therapy written by A Tefferi and others. Dr Tefferi is a world famous expert on myeloproliferative diseases. These authors have not found that treatment with hydrea and other cytoreductive drugs increases the risk for leukemic transformation.
http://www.nature.com/leu/journal/v2.../2404500a.html
Good that your father feels better after transfusion

!
Kind regards
Birgitta-A