Hi Trudy,
Nplate (AMG 531) has given increased blast cells in MDS patients

- don“t try that drug if you have MDS! Look at these lines:
"In a separate single-arm clinical study of 44 patients with myelodysplastic syndromes (MDS), 11 patients were reported as having possible disease progression, among whom 4 patients had confirmation of acute myelogenous leukemia (AML) during follow-up.
Nplate is not indicated for the treatment of thrombocytopenia due to MDS or any cause of thrombocytopenia other than chronic ITP."
http://www.drugs.com/nplate.html
Kind regards
Birgitta-A