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Originally Posted by Lynn del
What is IST? Thanks, Lynn
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IST = Immune Suppressant Therapy, i.e. ATG & cyclosporine.
Ken's had 2 rounds of ATG. The first time his Plts never got above about 30k on their own, and then he relapsed during the cyclo taper. For that reason (plus the fact that he has a trisomy 8 mutation), we haven't even attempted to taper him off the CsA this time, even though it's been over 3 years. He's still taking 175 mg/day (which is a concern), but the good news is that he has continued to show gradual improvement, with his Plts now over 115k and Hgb in normal range. It's been very slow progress, but we'll take it!