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some facilities are trying to either vidaza or dacogen over a 10 day period instead of the normal 5 or 7. for some reason, reducing the dose and doing it over a longer period sometimes has a better effect of promoting cell differentiation and lowering the marrow suppression. It may be worth discussing as an alternative. This is sometimes followed by a DLI to varying degrees of success.
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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