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Old Tue Aug 5, 2014, 06:22 PM
rar rar is offline
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Join Date: Mar 2014
Location: colorado
Posts: 215
BMB 1 Month post transplant question

I got my BMB report and I don't know what to think of it. On one hand it says No molecular evidence of residual host pre-transplantation cells is detectable, but host alleles are 12 to 32%.

My ANC went from 0 to 3.2, WBC went from 0 to 4.1 the highest they have been since a year before I was diagnosed with MDS. Hemoglobin from 7.8 to 11.4, and platelets from 11 to 57, had been as high as 75. These numbers seem encouraging.

Ray

INTERPRETATION:
Donor cells constitute approximately 68% of the cell population in the
CD3-enriched cell fraction, approximately 75% of the cell population in the
CD33-enriched fraction and approximately 88% of the CD56-enriched fraction of
the peripheral blood specimen from 07-30-14.
CHIMERISM MULTISPEC RESULTS:
Donor Alleles Host Alleles
Specimen: CD3 fraction Detected (Approx 68%) Detected (Approx 32%)
Specimen: CD33 fraction Detected (Approx 75%) Detected (Approx 25%)
Specimen: CD56 fraction Detected (Approx 88%) Detected (Approx 12%)
INFORM: The STR markers are informative for
both the pre-BMT host and donor
genomic DNA and can be used to monitor
bone marrow transplant engraftment.
NONINFOR: The STR markers would not be useful
for monitoring bone marrow transplant
engraftment.
NOMOLEC: No molecular evidence of residual host
pre-transplantation cells is detectable
by PCR in this specimen.
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