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Old Tue Dec 13, 2011, 01:43 AM
Chirley Chirley is offline
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Join Date: Oct 2007
Location: Logan City Australia
Posts: 1,100
Hi Catherine, that's a good question.

I asked the Prof the same thing. They don't know how many transport proteins there are let alone how they work or what other interactions they have.

That's part of the reason I became a bit down after my visit to him. He said that just because the blood copper levels are normal it doesn't mean the copper is being utilized in all the necessary places. There may be a transport protein missing that stops the copper from being utilized at cellular level.

Then I read an article about a man who had copper deficiency who didn't respond to copper replacement and ended up having brain stem involvement. He became blind and wheelchair bound despite treatment.

There is so little known about copper and it's metabolism that when i read an article like that, i have to accept that it's a possibility that it might happen to me. Fingers crossed it won't, but it is possible.

Regards
__________________
Copper deficiency bone marrow failure (MDS RAEB 1), neuromyelopathy.
FISH reported normal cytogenetics but gene testing showed
Xq 8.21 mutation
Xq19.36 mutation
Xq21.40. mutation
1p36. Mutation
15q11.2 deletion
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