Thread: Vidaza
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Old Sat Oct 11, 2014, 10:39 PM
DanL DanL is offline
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Join Date: Dec 2010
Location: Denver, CO
Posts: 590
@Cheryl,

Last I checked, RCMD is a classification under the WHO or WPSS classifications system. It is difficult to keep them all straight because doctors will use them interchangeably depending on what they are trying to tell you, but there are three other systems, two of which utilize a staging type of classification - the IPSS and the IPSS-R. The last system in use is the old French, American, British or FAB.

There is a pretty good resource right here on the forums, although it is missing the IPSS-R, which is a revised version of the IPSS and includes more prognostic data.

http://www.marrowforums.org/mds.html

Here is something on the IPSS-R

http://www.mdsbeacon.com/news/2012/0...ystem-decoded/

RCMD can be associated with a lower risk, intermediate risk, or high risk assessment, depending on blast percentage, chromosomal abnormalities, and severity of cytopenias associated with the dysplasia.

I started out as RCUD - only platelets affected, and moved to RCMD, which was accompanied by being considered low risk on the IPSS-R, but later moved to Intermediate-2 as the disease progressed prior to transplant, still being RCMD.

Hope that helps.
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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