Hi Umaterr,
I really don't understand how your husband can have high risk MDS when his blast cells are 3% that is a normal value. For high risk MDS the blast cells should be 5% or more.
http://www.marrowforums.org/mds.html
Then it is true that MDS after treatment for another malignant disease like myeloma is more dangerous and that his chromosome aberration isn't OK.
How old is your husband and does he have other diseases that can make a SCT more complicated?
Kind regards
Birgitta-A
75 yo, dx MDS Interm-1 (RCMD) 2006, Supportive therapy until 2010. Then treated with Thalidomide with positive response until 2013. Now taking Revlimid.