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Old Tue Jul 29, 2014, 06:25 PM
DanL DanL is offline
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Join Date: Dec 2010
Location: Denver, CO
Posts: 590
I am very sorry to hear about your husband's relapse. There have been a number of studies on using Vidaza along with DLI as a second line therapy for relapse after transplant, but because it is a fairly new approach, there aren't large numbers to work with, so any study done may not present all of the relevant facts as to success rates or improvements in the approach, or really the full demographic picture of why it works on one person and not another.

Here is the largest study I could find to date:

http://www.bloodjournal.org/content/122/21/4642
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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