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Old Sun Jan 12, 2014, 04:03 PM
DanL DanL is offline
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Join Date: Dec 2010
Location: Denver, CO
Posts: 590
Bailie,

Unfortunately, I have not had any real positive response thus far to Vidaza, but keep in mind that Vidaza can take up to 6 cycles to see an improvement for some patients. At 6 cycles, 91% of people who will respond, respond at that point. After 3 cycles, I believe that it is 70% of those who are going to respond, do. Every individual seems to be pretty darned unique when it comes to response, but the above are backed by the study below.

http://www.ncbi.nlm.nih.gov/pubmed/21656747

Do I feel better or worse? I would say that in general, I do not feel better, but the problem is that I may have felt worse regardless of starting Vidaza or not.

I turn 40 in February.

@ Diver Down's wife, I did read an interesting article the other night suggesting that 12% is a critical number of blasts at transplant, meaning that there was not a significant difference in survival between people who were under 12% vs 12% or more at transplant. The study was for AML patients, so it may not be fully applicable, but may be a guide.

http://link.springer.com/article/10....185-013-1312-1
__________________
MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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