Home         Forums  

Go Back   Marrowforums > Treatments > Drugs and Drug Treatments
Register FAQ Search Today's Posts Mark Forums Read

Drugs and Drug Treatments ATG, Cyclosporine, Revlimid, Vidaza, Dacogen, ...

Reply
 
Thread Tools Search this Thread
  #1  
Old Thu Jun 16, 2022, 08:13 PM
Johntand Johntand is offline
Member
 
Join Date: Jun 2022
Location: Baton Rouge, la
Posts: 2
ATG Treatment

My 22 year son was recently diagnosed with SAA. Began ATG and cyclosporine plus promacta on 5/30. Within the last few days he has excruciating pain in his knees. Dr. Believes it is from the bone stimulator shot that he received while in the hospital. Anyone have this issue and more importantly anything help alleviate the symptoms. The doctors have suggested Claritin but it doesn?t seem to help.
Reply With Quote
  #2  
Old Fri Jun 17, 2022, 02:16 AM
Neil Cuadra Neil Cuadra is offline
Owner
 
Join Date: Jul 2006
Location: Los Angeles, California
Posts: 2,556
Johntand,

I'm sorry to hear about you son's knee pain. Do you know more about the specific drugs and shots he received or is receiving?

I'm not an expert, but I'll tell you what I've read about this type of problem.

Did your son receive the GCSF (granulocyte colony-stimulating factor) drug named Neulasta (pegfilgrastim)? It can increase histamine, which can result in inflammation and pain. To counter this side effect, Claritin (loratadine) and/or Pepcid (famotidine) have been found to help some but not all patients. They aren't strong medicines, but they are safe to try.

If he's no longer receiving the treatment that caused the pain, this symptom could fade on its own. When it comes to side effects, it's the continuing treatments that are the highest concern. But of course pain like this is awful even if it's expected to be temporary.

It would be worth knowing any additional medicine, other than the ones you mentioned, that your son is receiving, such as Epogen (epoetin alfa), prednisone, etc. so you can be aware of all the side effects he might have to watch for.

To deal with the knee pain, you or your son could discuss, with the doctor, changing the treatment schedule or using stronger medicine to lessen this side effect.

And, just to be complete about the possibilities, pain can also be from causes unrelated to his SAA treatment or a separate medical condition that has resurfaced or has been exacerbated by the SAA treatment. But that doesn't seem especially likely if he's never had knee pain before.
__________________
Founder of Marrowforums and caregiver for my wife
Reply With Quote
  #3  
Old Fri Jun 17, 2022, 03:44 PM
Johntand Johntand is offline
Member
 
Join Date: Jun 2022
Location: Baton Rouge, la
Posts: 2
Yes. Pegfilgrastim is the drug. We spoke to the Dr. And he is going to move away from that given the pain and he will start taking Vantin. Also switched to atovaquone instead of penxamidine. Also backed off on the prednisone taper. Given all of that, you are right about the symptoms getting better. Last night was first night in a week that he was able to sleep pain free. Although he did take a heavy pain pill before he went to bed. Thank you.
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
ATG treatment completed ASQ AA 4 Sun Jun 10, 2018 04:01 AM
please share lymphocytes counts before ATG, day1 of ATG and after 1 month of ATG pvinod AA 16 Fri Dec 30, 2011 03:32 PM
3rd ATG treatment Janire AA 7 Wed Apr 13, 2011 03:57 PM
Need advice: how to decide if 2nd ATG treatment is worth it???????? susansr AA 3 Thu Jan 13, 2011 11:21 AM
Practicalities of ATG treatment? stephy AA 9 Thu Dec 31, 2009 01:49 PM


All times are GMT -4. The time now is 11:40 PM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org