Home         Forums  

Go Back   Marrowforums > Treatments > Drugs and Drug Treatments
Register FAQ Search Today's Posts Mark Forums Read

Drugs and Drug Treatments ATG, Cyclosporine, Revlimid, Vidaza, Dacogen, ...

Reply
 
Thread Tools Search this Thread
  #1  
Old Sun Feb 15, 2015, 02:51 AM
DanL DanL is offline
Member
 
Join Date: Dec 2010
Location: Denver, CO
Posts: 590
Rituxan

so i have completed six rounds of vidaza since August and just performed the third biopsy since then. we are waiting for the fish to come back next week before deciding whether to continue vidaza, take a break, or seek out additional treatments.

in the meantime, i have started the first of six to eight treatments with rituxan to combat refractory gvhd. i don't have severe gvhd in any one place, but i do have gvhd in several places and it seems to flare up periodically reassuring medication changes and steroids from time to time. rituxan has been used for refractory gvhd with some success from what i can tell, so here's to hoping for another success story.

you might be asking why do i need to get rid of the gvhd so badly if it is not too advanced. this is a great question, the primary answer being that it gives me more therapeutic options if i have another or stronger relapse. the consensus is that donor lymphocyte infusion would push any gvhd over the top and add a lot of risk if the gvhd is not fully under control prior to adding more potentially hostile donor cells.

fortunately rituxan is a pretty easy treatment on the scale of things and day one cycle one was a piece of cake.
__________________
MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
Reply With Quote
  #2  
Old Sun Feb 15, 2015, 04:54 AM
Birgitta-A Birgitta-A is offline
Member
 
Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
GVHD

Hi Dan!
Hope the Fish test will be OK and that Rituxan will have positive effect!

Good to read about a member that probably is cured even if you have GVHD!
Kind regards
Birgitta-A
Reply With Quote
  #3  
Old Sun Feb 15, 2015, 09:12 AM
bailie bailie is offline
Member
 
Join Date: Dec 2013
Location: McMinnville,OR
Posts: 825
Great to hear from you Dan, I follow your comments closely since you are a step ahead of me. I continue to hope you feel well. It is interesting. I am always interested in your Vidaza situation because eventually that will most likely be in my future when something comes up.
__________________
age 70, dx RAEB-2 on 11-26-2013 w/11% blasts. 8 cycles Vidaza 3w/Revlimid. SCT 8/15/2014, relapsed@Day+210 (AML). Now(SCT-Day+1005). Prepping w/ 10 days Dacogen for DLI on 6/9/2017.
Reply With Quote
  #4  
Old Sun Feb 15, 2015, 06:03 PM
DanL DanL is offline
Member
 
Join Date: Dec 2010
Location: Denver, CO
Posts: 590
@bailie,

i always pray that other members of the forum follow the easiest path possible, so i am hoping that you will not require any additional treatment, so i am hoping not to be the role model in this case, but appreciate the support along the way.

@birgitta,

you are one of the biggest inspirations and very much the soul of this forum, so it is always an honor to receive a post from you. i think it is early to use the c word, but we are hopeful.
__________________
MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
Reply With Quote
  #5  
Old Mon Feb 16, 2015, 12:25 PM
Birgitta-A Birgitta-A is offline
Member
 
Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
MDS

Hi Dan!
Thank you for the kind words. You know it is important for many members to read about very positive results because most of us can't be so hopeful.
Kind regards
Birgitta-A
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Boost for low blood counts Data Transplants 12 Fri Nov 4, 2016 08:46 PM
Possible Relapse DanL Transplants 10 Sat Feb 28, 2015 11:53 AM
Julie's Adventure Julianna Tell Your Story 35 Sat Jan 29, 2011 02:09 AM


All times are GMT -4. The time now is 06:50 AM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org