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Drugs and Drug Treatments ATG, Cyclosporine, Revlimid, Vidaza, Dacogen, ...

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Old Fri Dec 12, 2014, 03:37 AM
Birgitta-A Birgitta-A is offline
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GVHD

Hi All!
Here is info about how to try to avoid GVHD.
http://www.bloodjournal.org/content/124/25/3672
Kind regards
Birgitta-A
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Old Fri Dec 12, 2014, 01:05 PM
Neil Cuadra Neil Cuadra is offline
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This is a very promising result. It compares cyclophosphamide alone, rather than in combination with methotrexate or sirolimus, for preventing graft-versus-host disease after a stem cell transplant with matched related or unrelated donors.

When cyclophosphamide is used alone, it is reportedly good at reducing unwanted T cells without harming "good" T cells, and that's a key to avoiding GVHD. Overall, 87% of their study subjects avoided chronic GVHD.
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